Explaining hereditary hemochromatosis

An iron buildup in the body of hemochromatosis sufferers requires regular blood draws until iron levels are normal. Still, their blood is safe to use as donor blood for others, Dr. Keith Roach notes.

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Lifestyle

October 19, 2022 - 2:16 PM

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DEAR DR. ROACH: My 45-year-old son has hemochromatosis. The treatment is phlebotomy of a pint of blood, sometimes every two weeks, until the iron level is normalized. My understanding is that the blood is discarded. Is there anything wrong with the blood?  — E.B.

ANSWER: Hereditary hemochromatosis is caused by the body absorbing too much iron due to a genetic defect. With no way to get rid of iron, it builds up and damages many organs, especially the heart, bone marrow, joints and adrenal gland. 

The best treatment is to remove iron in the form of red blood cells. This is effective at preventing most of the organ damage, if started quickly enough.

There has never been anything wrong with the blood of people with hereditary hemochromatosis, and the FDA here in the U.S. has always allowed the blood to be donated. However, until recently, the American Red Cross has not accepted blood donations from people with hereditary hemochromatosis. I am pleased to say that they have just changed their policy and will now be using this precious resource to help others, so long as the person meets all the criteria for being a blood donor. The blood will undergo all the standard and rigorous testing prior to being pronounced safe for use.

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